Cinnamic acid is a pure compound discovered in lots of crops and the widespread spice cinnamon (
It could have anti-inflammatory properties and be linked to well being advantages, reminiscent of decrease blood sugar ranges, improved reminiscence, and a decreased likelihood of creating cancerous tumors (
This text opinions cinnamic acid, together with its advantages, potential negative effects, and meals sources.
Cinnamic acid is a pure, protecting plant compound present in cinnamon bark, ginseng, entire grains, and honey, amongst different meals (
It’s derived when the amino acid, phenylalanine, is damaged down by enzymes (
It has over 50 derivatives and is a possible therapeutic compound. A current examine discovered that it could be corresponding to, or much more potent than, normal medicine used to deal with some persistent and infectious ailments like tuberculosis (
Cinnamic acid additionally has industrial makes use of and is a typical ingredient in beauty merchandise, reminiscent of perfumes and pores and skin lotions, by which it’s used for its ultraviolet (UV) safety and anti-aging properties (
Abstract
Cinnamic acid is a naturally occurring compound discovered in lots of crops, together with cinnamon bark. It has potential therapeutic advantages for persistent and infectious ailments and is a typical ingredient in beauty merchandise.
Laboratory, animal, and human research have all indicated that cinnamic acid might provide a number of well being advantages.
Could enhance intestine well being
Intestine well being refers back to the bodily well being of the intestinal tract, together with the flexibility to adequately digest meals and take up its vitamins. It additionally refers back to the intestine microbiota, which is the neighborhood of micro organism that stay within the intestine.
Poor intestine well being and dysbiosis — the overgrowth of “dangerous” micro organism within the intestine — are related to inflammatory situations reminiscent of most cancers, obesity, coronary heart illness, and kind 2 diabetes (
Cinnamic acid is 1 of 14 spice extracts with prebiotic potential, which means that it has been proven to advertise the expansion of “good” micro organism within the intestine whereas suppressing the expansion of “dangerous” micro organism in lab research (
Moreover, a 2020 examine confirmed that cinnamic acid inhibited the expansion of E. Coli (GUS) within the intestine — a pressure of micro organism related to meals poisoning (
Could enhance reminiscence and mind well being
One examine in mice with diabetes demonstrated that injections with cinnamic acid improved markers of dementia-related reminiscence impairment (
The impact was dose-dependent, which implies that the extra cinnamic acid that was injected into the mice, the extra their reminiscence improved (
One other examine confirmed that cinnamic acid has a protecting impact over the dopamine-producing neurons in mice with Parkinson’s illness (
The lack of dopamine-producing neurons is attribute of Parkinson’s illness, the second commonest age-related neurodegenerative dysfunction (
Cinnamon extracts, together with cinnamic acid, may additionally forestall the buildup of beta-amyloid (Aβ) peptides, which play an necessary position within the development of Alzheimer’s disease (
Though these animal research present nice potential, extra human analysis is required.
Could scale back the chance of creating diabetes
Type 2 diabetes mellitus is a fancy metabolic dysfunction that’s prevalent in kids and adults (
Moreover, diabetes is an inflammatory situation that’s related to oxidative stress and an elevated danger of coronary heart illness (
Cinnamic acid has antioxidant and anti inflammatory properties. It could enhance blood markers of diabetes by enhancing cells’ uptake of glucose and lowering the liver’s manufacturing of glucose (
Cinnamic acid additionally improved blood cholesterol levels in mice with diabetes (
Different potential well being advantages:
Research present that cinnamic acid might produce other well being advantages as properly:
- Could deal with periodontitis. Periodontitis is irritation of the gum tissue, and periodontal illness has been linked to ailments of the cardiovascular, endocrine, and reproductive methods. One rat examine found that cinnamic acid decreased irritation attributable to periodontitis and promoted bone development within the space (
19 ,20 ). - Potential most cancers remedy. Research have proven that cinnamic acid and its derivatives inhibit cancer-causing proteins and could also be an adjunct remedy for the remedy of lung and breast cancers (
21 ,22 ). - Could provide UV safety. Cinnamic acid is a typical ingredient in lots of beauty merchandise, by which it’s used to supply UV safety. Cinnamic acid is delicate to and activated by UV radiation, providing antioxidant advantages (
4 ,23 ). - Could scale back the chance of dengue. Some derivatives of cinnamic acid have larvicidal properties and have been proven to destroy the larvae of the Aedes aegypti mosquito, which transmits dengue, yellow fever, and the Chikungunya and Zika viruses (
24 ).
It’s necessary to notice that many of those research have been carried out on remoted human cells in lab research or on animals, reminiscent of mice.
Due to this fact, well-designed analysis and medical trials are wanted to substantiate whether or not cinnamic acid would have the identical results in people (
Abstract
Cinnamic acid has been related to numerous well being advantages and should help intestine well being and reminiscence. It could assist forestall neurodegeneration, diabetes, most cancers, and periodontal illness. But, extra analysis is required.
Cinnamic acid is usually protected for people when consumed within the small quantities current in meals.
Nevertheless, the excessive concentrations of cinnamic acid found in some cosmetic products can set off allergic reactions and dermatitis irritation of the pores and skin in some individuals (
These cosmetics manufacturers are both required to make use of smaller doses or print a security warning on the label (
There’s additionally concern that UV filters in cosmetics and sunscreens — together with the natural compound cinnamic acid — enter the marine setting and are dangerous (
Poisonous environmental results to marine organisms, reminiscent of sea urchins, fish, coral, and algae, embrace inhibited development and replica, malformations, and demise (
Moreover, there’s a potential toxicity concern for cinnamaldehyde — a compound present in cinnamon that may probably be transformed to cinnamic acid within the physique (
Total, analysis information on the protection of cinnamic acid is scant. Extra analysis is required to find out its correct dosage and security profile.
Abstract
Cinnamic acid is usually protected when consumed within the small quantities naturally current in meals. The excessive concentrations of cinnamic acid in beauty merchandise might set off allergic reactions and be poisonous to the marine setting.
Cinnamic acid is of course present in a spread of crops and spices. These crops additionally present different important nutritional vitamins and minerals wanted for general good well being.
You may get cinnamic acid from (
- cinnamon bark (together with bark oil, bark powders, and cinnamon stick)
- ginseng (Panax ginseng)
- balsam tree sap
- fruits
- greens
- entire grains (cereal grains, rice, wheat bran)
- honey
There are not any identified cinnamic acid dietary supplements presently.
Abstract
Cinnamic acid is present in quite a lot of plant sources, together with cinnamon bark and its merchandise, ginseng, fruits, greens, honey, and entire grains reminiscent of rice, wheat bran, and cereal grains.
Cinnamic acid is a pure compound present in quite a lot of crops sources, together with cinnamon bark.
It’s linked to many potential well being advantages, together with decreased irritation, decrease blood sugar and levels of cholesterol, improved reminiscence, and the elevated development of “good” intestine micro organism.
Whereas scant information exists on its security, it seems to be protected when consumed within the small quantities naturally present in meals. That mentioned, there are potential allergy and toxicity dangers associated to the excessive concentrations of this compound present in beauty merchandise.
Extra analysis is required on the usage of cinnamic acid.