Tagrisso could cause delicate or critical unintended effects. The next lists comprise a few of the key unintended effects that will happen whereas taking Tagrisso. These lists don’t embody all potential unintended effects.
For extra details about the potential unintended effects of Tagrisso, discuss together with your physician or pharmacist. They may give you recommendations on easy methods to handle any unintended effects which may be regarding or bothersome.
Be aware: The Meals and Drug Administration (FDA) tracks unintended effects of medicine it has authorised. If you want to inform the FDA a few aspect impact you’ve had with Tagrisso, you are able to do so by means of MedWatch.
Gentle unintended effects
Gentle unintended effects* of Tagrisso can embody:
Most of those unintended effects might go away inside just a few days or a few weeks. Nonetheless, in the event that they develop into extra extreme or don’t go away, discuss together with your physician or pharmacist.
* It is a partial record of delicate unintended effects from Tagrisso. To study different delicate unintended effects, discuss together with your physician or pharmacist, or view Tagrisso’s prescribing information.
† For extra details about this aspect impact, see “Aspect impact particulars” beneath.
Critical unintended effects
Critical unintended effects from Tagrisso can happen. Name your physician immediately when you have critical unintended effects. Name 911 or your native emergency quantity in case your signs really feel life threatening or should you suppose you’re having a medical emergency.
Critical unintended effects and their signs can embody:
* For extra details about this aspect impact, see “Aspect impact particulars” beneath.
Aspect impact particulars
Right here’s some element on sure unintended effects this drug might trigger.
Pores and skin rash and different pores and skin issues
Some folks might develop a light or critical skin rash whereas taking Tagrisso. It might probably additionally trigger different pores and skin issues listed beneath.
In clinical trials, delicate pores and skin issues have been widespread with Tagrisso. Critical pores and skin rashes have been much less generally reported. To be taught extra about how usually this aspect impact occurred in medical trials, see the drug’s prescribing information.
Examples of delicate pores and skin issues reported with Tagrisso embody:
Examples of great pores and skin rashes which were reported with Tagrisso and their signs embody:
- Stevens-Johnson syndrome (widespread painful rash affecting the pores and skin and mucous membranes [moist tissue lining your mouth, throat, eyes, nose, and genitals]). Signs can embody:
- extreme blisters adopted by peeling of the pores and skin and mucous membranes
- Erythema multiforme (pores and skin response brought on by an immune response to a viral an infection). Signs can embody:
- raised purple, purple, or discolored rash affecting the pores and skin and mucous membranes
- ring-shaped spots that seem like targets
- sore mouth, throat, and eyes
- Cutaneous vasculitis (inflammation of the blood vessels in your pores and skin). Signs can embody:
- purple, purple, or darkish spots in your forearms, decrease legs, or buttocks that final over 24 hours
- giant hives or bruises in your physique that final over 24 hours
In case you have a light however troublesome pores and skin drawback whereas taking Tagrisso, discuss together with your physician. They will advocate methods to deal with the issue.
Some critical pores and skin rashes may be life threatening and might have therapy within the hospital. In case you have signs of a critical pores and skin rash whereas taking Tagrisso, contact your physician immediately. Your physician might advocate you cease taking Tagrisso whereas they verify to see what’s inflicting the rash. In case your physician confirms you will have a critical rash, they’ll have you ever cease taking Tagrisso completely.
Lung issues, comparable to pneumonitis
Tagrisso can typically trigger critical lung issues, comparable to pneumonitis and interstitial lung disease (ILD). Pneumonitis is inflammation (irritation and swelling) within the air sacs of your lungs. ILD is irritation that causes scar tissue to kind in your lungs.
In clinical trials, critical lung issues weren’t a standard aspect impact of Tagrisso therapy. To be taught extra about how usually this aspect impact occurred in medical trials, see the drug’s prescribing information.
Signs of great lung issues may be much like signs of lung cancer. (Tagrisso is taken to deal with sure sorts* of non-small cell lung cancer). Signs might embody:
Critical lung issues may be life threatening.In case you have any new or worsening lung signs whereas taking Tagrisso, contact your physician immediately. Your physician might advocate you cease taking Tagrisso whereas they verify to see what’s inflicting your signs. In case your physician confirms you will have pneumonitis or ILD, they’ll have you ever cease taking Tagrisso completely.
* For extra info on the circumstances that Tagrisso is taken to deal with, see “Tagrisso uses” beneath.
Hair loss
Some folks might have some hair loss or hair thinning whereas taking Tagrisso. Nonetheless, hair loss wasn’t a standard aspect impact reported in clinical trials of Tagrisso. To be taught extra about how usually this aspect impact occurred in medical trials, see the drug’s prescribing information.
It’s vital to notice that hair loss is a standard aspect impact of different cancer treatments. These embody chemotherapy and radiation therapy. Your physician might prescribe these therapies to deal with your lung cancer.
In case you have hair loss that’s bothersome to you, discuss together with your physician. They will advocate methods to assist handle this aspect impact.
Ocular (eye) unintended effects
Tagrisso could cause an ocular (eye) aspect impact referred to as keratitis. Keratitis is inflammation (irritation and swelling) of the cornea (clear entrance layer of your eye).
Keratitis was a uncommon aspect impact in clinical trials of Tagrisso. To be taught extra about how usually this aspect impact occurred in medical trials, see the drug’s prescribing information.
Signs of keratitis might embody:
If not handled, keratitis can result in the formation of ulcers (sores) or scars in your cornea. This might trigger blindness in uncommon circumstances.
In case you have signs of keratitis whereas taking Tagrisso, contact your physician immediately. They’ll seemingly refer you to a watch specialist. They might advocate that you simply cease taking Tagrisso whereas the situation is handled.
ALLERGIC REACTION
As with most medicine, some folks can have an allergic reaction after taking Tagrisso.
Signs of a light allergic response can embody:
A extra extreme allergic response is uncommon however potential. Signs of a extreme allergic response can embody:
- swelling below your pores and skin, sometimes in your eyelids, lips, palms, or ft
- swelling of your tongue, mouth, or throat
- hassle respiration
Name your physician immediately when you have an allergic response to Tagrisso, because the response may develop into extreme. Name 911 or your native emergency quantity in case your signs really feel life threatening or should you suppose you’re having a medical emergency.
