Writing in Cosmetic Dermatology, researchers from Turkey’s Düzce College developed a prototype skincare product utilizing bee venom, propolis, honey, beeswax and royal jelly and analysed stability, antioxidant exercise, dermatological response and cytotoxicity. The researchers then evaluated product claims round pores and skin smoothness, nourishment, moisturisation, pores and skin tone, brightness, and wrinkle visibility in a small-scale panel research.
Total, findings confirmed {that a} physique cream made utilizing a mix of bee venom and different bee merchandise (0.1% bee venom, 0.3% propolis extract, 0.45% honey and 1% royal jelly) had a “excessive antioxidant capability” at 85.45%. As well as, the components proved to be non-cytotoxic, with no irritation or allergic response in non-allergic people, enabling it to be labeled as non-irritating.
“Panel take a look at(ing) confirmed that the prototype makes pores and skin silky clean, contributes to hydration, brightens and nourishes the pores and skin, evens the pores and skin tone, reduces the visibility of wrinkles, improves pores and skin elasticity, and smooths wrinkles,” the researchers wrote.
Additional testing could be required to judge effectiveness in opposition to pores and skin ageing on completely different pores and skin sorts, they mentioned, given testing had solely been carried out on a really small panel quantity (10 ladies). Wider research would additionally present extra perception on the degrees of bee venom that could possibly be included into formulation for efficient anti-ageing properties.
Past wholesome pores and skin ageing, the researchers mentioned the bee product mix may be investigated for UV safety and as a possible choice to deal with zits.
‘Excessive antioxidant exercise’ of bee product elements
The researchers mentioned incorporating bee venom right into a physique care topical components was significantly attention-grabbing given it was a “pharmacologically energetic hive product” already related to therapeutic in opposition to sure pores and skin ailments like atopic dermatitis and recognised for its antimicrobial exercise in opposition to zits vulgaris. Bee venom had additionally been confirmed to be a photoprotective agent.
“Bee venom may be an exceptionally helpful pure ingredient for the cosmetics business via its anti-inflammatory exercise and wound therapeutic properties,” the researchers wrote.
Importantly, when utilized in mixture with different bee merchandise, notably propolis, the tip components provided “excessive antioxidant exercise” – a big benefit for the cosmetics sector trying to develop anti-ageing formulations, they mentioned. This excessive antioxidant exercise additionally provided stability and storage assurances, with assessments indicating the product could possibly be used for 12 months after opening with no affect to color or look.
Propolis was additionally a “sturdy adhesive” with varied organic actions – antioxidant, anti-inflammatory, antiviral and antifungal – and equally recognised for its therapeutic properties and safety in opposition to the dangerous results of UV gentle and free radicals. Royal jelly was related to potential safety in opposition to UVB-induced photograph and pores and skin ageing by growing collagen manufacturing and honey labored to melt, moisturise and clean pores and skin.
Allergenicity warnings – bee venom reactions
Nonetheless, the researchers mentioned “specific consideration” must be made in any commercialisation of such a product due to the unwanted side effects related to bee venom in sure prone people.
While there was a “rising curiosity within the features of bee venom within the cosmetics discipline”, they mentioned any product would want very clear on-pack declarations made in regards to the quantity and particular elements of the product.
Supply: Beauty Dermatology
Printed on-line forward of print, March 2, 2022 – doi.org/10.1111/jocd.14891
Title: “Growth of a cream formulation containing bee venom and different bee merchandise”
Authors: AET. Samanci and M. Kekeçoğlu
