Libtayo could cause delicate or severe uncomfortable side effects. The next lists comprise a number of the key uncomfortable side effects that will happen whereas receiving Libtayo. The drug’s uncomfortable side effects would possibly differ barely relying on whether or not Libtayo is getting used to deal with pores and skin most cancers or lung most cancers.
These lists don’t embody all potential uncomfortable side effects. For extra details about the potential uncomfortable side effects of Libtayo, speak along with your physician or pharmacist. They may give you tips about learn how to handle any uncomfortable side effects which may be regarding or bothersome.
Observe: The Meals and Drug Administration (FDA) tracks uncomfortable side effects of medication it has authorized. If you need to inform the FDA a few aspect impact you’ve had with Libtayo, you are able to do so by means of MedWatch.
Gentle uncomfortable side effects
Gentle uncomfortable side effects* of Libtayo can embody:
Most of those uncomfortable side effects might go away inside just a few days or a few weeks. But when they change into extra extreme or don’t go away, speak along with your physician or pharmacist.
* It is a partial listing of delicate uncomfortable side effects from Libtayo. To study different delicate uncomfortable side effects, speak along with your physician or pharmacist, or view Libtayo’s prescribing information.
† For extra details about this aspect impact, see “Facet impact particulars” under.
Critical uncomfortable side effects
Critical uncomfortable side effects can happen in some folks throughout Libtayo therapy. Name your physician straight away in case you have severe uncomfortable side effects. Name 911 or your native emergency quantity in case your signs really feel life threatening or for those who suppose you’re having a medical emergency.
Critical uncomfortable side effects and their signs can embody:
- High blood pressure. Signs don’t usually happen, however very hypertension might trigger:
- Critical infections, equivalent to pneumonia or cellulitis (bacterial pores and skin an infection). Signs range however can embody:
- areas of pores and skin which can be swollen, painful, or have sores
- cough that will produce yellow or inexperienced mucus
- Blood issues, equivalent to lymphopenia (low degree of lymphocytes) and anemia (low pink blood cells). Signs can embody:
- elevated threat of an infection with lymphopenia
- fatigue, dizziness, or wanting extra pale than typical with anemia
- Different modifications in blood take a look at outcomes, together with modifications in ranges of electrolytes, equivalent to sodium, phosphate, and potassium. Signs can embody:
- Infusion-related response.*
- Immune-mediated response*
- Allergic reaction.*
* For extra details about this aspect impact, see “Facet impact particulars” under.
Facet impact particulars
Listed here are some particulars about sure uncomfortable side effects this drug might trigger. To learn how usually uncomfortable side effects occurred in scientific trials, see the prescribing information for Libtayo.
Infusion-related response
A healthcare skilled will give Libtayo as an intravenous (IV) infusion. That is an injection right into a vein given over a time frame. Libtayo infusions normally final about half-hour. It’s potential to have uncomfortable side effects in the course of the infusion. These are known as infusion-related reactions.
Signs of infusion-related reactions might embody:
- nausea
- fever
- pores and skin rash
- wheezing or hassle respiration
- shaking or chills
- flushing
- dizziness
- feeling such as you would possibly faint
The healthcare skilled will monitor you when you obtain your infusion. Inform them straight away in case you have any signs. They could decelerate or pause the infusion. You probably have a extreme infusion-related response, equivalent to hassle respiration, your physician might have you ever cease Libtayo therapy. In clinical trials, extreme infusion-related reactions have been uncommon.
You probably have questions on infusion-related reactions from Libtayo, speak along with your physician.
Fatigue
Fatigue is a potential aspect impact of Libtayo. It was one of many extra widespread uncomfortable side effects seen within the drug’s clinical trials.
With fatigue, chances are you’ll really feel weak and drained even for those who get your typical quantity of sleep.
If this aspect impact doesn’t go away or turns into extreme, speak along with your physician. They could recommend methods to spice up your vitality degree, equivalent to a every day stroll or power coaching (in accordance with your skill).
Muscle or bone ache
Libtayo might trigger ache in muscle tissue or bones. This aspect impact was generally seen in individuals who took Libtayo in clinical trials. Some folks additionally reported ache or stiffness of their joints, neck, and again.
The severity of the muscle or bone ache can range from delicate to extreme.
Discuss along with your physician in case you have ache that’s extreme or doesn’t go away. They could recommend methods to handle this aspect impact, equivalent to making an attempt bodily remedy or ache remedy. Over-the-counter ache drugs can embody acetaminophen (Tylenol). Prescription ache relievers can embody opioids, equivalent to hydromorphone (Dilaudid).
Immune-mediated response
Libtayo treats sure varieties of most cancers by working along with your immune system. In some circumstances, the drug might trigger your immune system to mistakenly assault your wholesome tissues and organs. This may increasingly result in inflammation and harm within the affected tissues or organs. Medical doctors name this an “immune-mediated” response.
Immune-mediated reactions weren’t widespread in clinical trials. Once they did happen, the uncommon circumstances have been severe and, at instances, deadly. In some folks, immune-related reactions have been reported after Libtayo therapy ended.
The signs of immune-mediated reactions differ from typical allergic response signs, equivalent to pores and skin rash. And so they range relying on which tissues and organs are affected.
Listed here are some examples of immune-mediated reactions than might happen with Libtayo:
- Pneumonitis (irritation of the lungs). Signs can embody:
- Hepatitis (irritation of the liver). Indicators and signs can embody:
- ache on the precise aspect of your stomach
- Colitis (irritation of the decrease gut). Signs can embody:
- bowel actions which can be looser or extra frequent than typical
- Nephritis (irritation of the kidneys). Signs can embody:
- producing much less urine than typical
- swelling of your decrease legs or ankles
- Thyroid problems. Signs might embody:
- weight acquire or weight reduction
Name your physician straight away in case you have any of those signs with Libtayo. The extra rapidly you obtain therapy for these reactions, the much less seemingly they’re to change into severe. Relying on the severity, your physician might pause or cease your Libtayo therapy. They could additionally suggest remedy to assist cease the response. For instance, a corticosteroid equivalent to prednisone (Rayos).
Allergic response
As with most medicine, some folks can have an allergic reaction after receiving Libtayo.
Signs of a light allergic response can embody:
A extra extreme allergic response is uncommon however potential. Signs of a extreme allergic response can embody:
- pores and skin peeling or blistering
- swelling beneath your pores and skin, usually in your eyelids, lips, fingers, or toes
- swelling of your tongue, mouth, or throat
- hassle respiration
Name your physician straight away in case you have an allergic response to Libtayo, because the response might change into extreme. Name 911 or your native emergency quantity in case your signs really feel life threatening or for those who suppose you’re having a medical emergency.
