Like most medication, Ibrance might trigger delicate or critical uncomfortable side effects. The lists under describe a number of the extra widespread ones. These lists don’t embody all doable uncomfortable side effects.
Ibrance is taken with sure different medicines. The uncomfortable side effects of Ibrance can fluctuate relying on the remedy you’re taking it with.
Understand that uncomfortable side effects of a drug can rely on:
- your age
- different well being circumstances you may have
- different medicines you’re taking
Your physician or pharmacist can let you know extra in regards to the potential uncomfortable side effects of Ibrance. They could additionally counsel methods to assist with managing the uncomfortable side effects of Ibrance.
Gentle uncomfortable side effects
Right here’s an inventory of a number of the delicate uncomfortable side effects Ibrance could cause. To study different delicate uncomfortable side effects, discuss along with your physician or pharmacist, or learn the prescribing data for Ibrance tablets and capsules.
Gentle uncomfortable side effects of Ibrance which were reported embody:
Gentle uncomfortable side effects of many medication might go away inside a couple of days to a few weeks. But when they turn into bothersome, discuss along with your physician or pharmacist. They could counsel methods to forestall or handle sure uncomfortable side effects.
* For extra details about this aspect impact, see the “Facet impact focus” part under.
Severe uncomfortable side effects
Severe uncomfortable side effects from Ibrance can happen. When you have critical uncomfortable side effects from this drug, name your physician immediately. When you suppose you’re having a medical emergency, you must name 911 or your native emergency quantity.
Severe uncomfortable side effects of Ibrance which were reported embody:
* For extra details about this aspect impact, see the “Facet impact focus” part under.
Facet impact focus
Study extra about a number of the uncomfortable side effects Ibrance might trigger.
Hair loss
Hair loss is likely one of the extra widespread uncomfortable side effects of Ibrance. Regardless that this aspect impact is widespread, it’s normally delicate.
Hair loss was reported as delicate in research of Ibrance tablets and capsules. It’s probably that the drug might trigger the hair in your head to turn into thinner, however not fall out utterly.
What may assist
It is probably not doable to prevent hair thinning or hair loss from Ibrance. You might contemplate attempting over-the-counter scalp remedies that include minoxidil, resembling Rogaine. And carrying a wig or different head masking may enable you really feel extra comfy.
When you have questions or issues about hair loss whereas taking Ibrance, discuss along with your physician.
Neutropenia
Taking Ibrance generally causes sure blood disorders (adjustments in your blood cell ranges as seen on blood exams).
The commonest aspect impact reported in research of Ibrance tablets and capsules was neutropenia. This refers to low ranges of a kind of white blood cell known as neutrophils.
Neutrophils work in your immune system to search out and destroy germs that will trigger infections, resembling micro organism. With out sufficient neutrophils, you’re extra prone to develop delicate or critical infections. Some examples embody widespread colds, urinary tract infections (UTIs), and the flu.
Signs of infections can fluctuate however might embody:
- fever*
- chills
- physique aches
- cough
- stuffy or runny nostril
What may assist
As a result of neutropenia is widespread with Ibrance, it’s necessary to take precautions to guard your self in opposition to infections whereas taking the drug. Some ideas embody washing your palms typically and avoiding contact with individuals who could also be sick.
To observe for neutropenia and different blood issues, your physician will organize blood exams. You’ll have a blood check known as a complete blood count (CBC):
- earlier than you begin taking Ibrance
- in the beginning of every 28-day therapy cycle
- on day 15 of your first 2 therapy cycles
- every time your physician recommends it throughout your therapy
If extreme neutropenia happens, your physician might have you ever pause Ibrance and resume it at a decrease dosage, or have you ever cease the drug. They could additionally advocate a therapy resembling pegfilgrastim (Neulasta) to extend your white blood cell ranges. You shouldn’t change your Ibrance dosage with out your physician’s approval, although.
Not often, Ibrance therapy might result in febrile neutropenia (neutropenia that happens together with a fever). In research of Ibrance tablets and capsules, febrile neutropenia led to 1 demise. When you develop a fever whereas taking Ibrance, inform your physician immediately.
Rash
You might develop a skin rash whereas taking Ibrance. This was one of many extra widespread uncomfortable side effects seen in folks taking Ibrance tablets and capsules in research.
Signs of a rash from Ibrance might embody:
- itchiness
- redness or swelling
- blistering
- pores and skin bumps that look much like zits
What may assist
When you get a rash whereas taking Ibrance, it’s greatest to inform your physician. They can assist decide if you happen to could possibly be having an allergic response.
Normally, a rash is a light aspect impact of Ibrance and never an allergic reaction. However since allergic reactions can shortly turn into extreme, it’s necessary to inform your physician a couple of rash or different pores and skin signs immediately.
In lots of circumstances, rash signs might be managed with over-the-counter cures. For instance, your physician or pharmacist might advocate making use of hydrocortisone cream to alleviate signs.
Allergic response
Some folks might have an allergic reaction to Ibrance. It’s not clear how many individuals had allergic reactions in research of Ibrance tablets or capsules.
Signs of a light allergic response can embody:
A extra extreme allergic response is uncommon however doable. Signs of a extreme allergic response can embody swelling below your pores and skin, sometimes in your eyelids, lips, palms, or toes. They will additionally embody swelling of your tongue, mouth, or throat, which may trigger bother respiratory.
Name your physician immediately if in case you have an allergic response to Ibrance. However if you happen to suppose you’re having a medical emergency, name 911 or your native emergency quantity.
