What Is Microzide?
Microzide (hydrochlorothiazide) is a prescription drug belonging to a category of medicines known as thiazide diuretics, additionally generally known as “water capsules.” It’s used to deal with hypertension (hypertension) and fluid retention (edema) attributable to sure circumstances.
It’s not precisely identified how hydrochlorothiazide works, however it’s thought to take away additional salt and water from the physique by rising urine movement. By doing this, hydrochlorothiazide retains your coronary heart from working too onerous to pump blood which lowers blood strain and reduces swelling.
Finally, the speed at which your coronary heart pumps blood returns to regular, and the peripheral vascular resistance is diminished, which results in a continued lower in blood strain.
Microzide is out there in pill and capsule kind.
Drug Information
- Generic Title: Hydrochlorothiazide
- Model Title(s): Microzide, Aquazide H, Hydrocot, Zide
- Administration Route(s): Oral
- Drug Availability: Prescription
- Therapeutic Classification: Cardiovascular agent
- Accessible Generically: Sure
- Managed Substance: N/A
- Energetic Ingredient: Hydrochlorothiazide
- Dosage Type(s): Pill, capsule
What Is Microzide Used For?
Hydrochlorothiazide is usually prescribed to deal with high blood pressure.
It’s also used to deal with edema that’s attributable to:
- Heart failure
- Liver injury
- Kidney issues
- Taking different drugs (e.g., corticosteroids or estrogens)
How one can Take Microzide
Microzide is out there as an oral pill or capsule. These are supposed to be taken by mouth. How usually you are taking Microzide relies on what situation you might be utilizing it to deal with and the way your physique reacts to the treatment.
You’ll be able to take this treatment with or with out meals.
Storage
Retailer hydrochlorothiazide at a managed room temperature, which is about 68 F to 77 F.
If touring, at all times carry your treatment with you. In case you are flying, be certain that to maintain the unique prescription-labeled bottle or field in your carry-on bag. Don’t go away this treatment in your automobile, particularly if the climate could be very chilly or scorching.
How Lengthy Does Microzide Take to Work?
Microzide will begin to work inside two hours of taking it. It is best to discover its full results after about 4 hours.
What Are the Aspect Results of Microzide?
This isn’t an entire checklist of unintended effects and others might happen. A medical skilled can advise you on unintended effects. When you expertise different results, contact your pharmacist or a medical skilled. You might report unintended effects to the FDA at www.fda.gov/medwatch or 1-800-FDA-1088.
Like most drugs, hydrochlorothiazide could cause delicate or extreme unintended effects.
Frequent Aspect Results
The most typical unintended effects with hydrochlorothiazide embody:
- Low blood pressure (hypotension)
- Dizziness
- Headache
- Weak point
- Tingling in your fingers, ft, and legs
- Erectile dysfunction
- Photosensitivity
Discuss to your healthcare supplier or pharmacist if any of those unintended effects don’t go away or turn out to be extra extreme.
Extreme Aspect Results
Contact your healthcare supplier immediately if in case you have severe unintended effects. Name 911 in case your signs really feel life-threatening or if you happen to suppose you’ve a medical emergency.
Severe unintended effects and their signs can embody the next:
- Allergic reactions with signs akin to rash, shortness of breath, hives, or swelling of the mouth, tongue, or lips
- Kidney failure with signs akin to weak point, confusion, shortness of breath, chest ache, producing much less urine than regular, and elevated swelling in your legs, ankles, or ft
- Pores and skin reactions akin to Stevens-Johnson syndrome with signs akin to painful rash, pores and skin blisters, fever, and mouth sores
- Blurred imaginative and prescient
Dosage: How A lot Microzide Ought to I Take?
Drug Content material Supplied and Reviewed by IBM Micromedex
The dose of this drugs will likely be totally different for various sufferers. Observe your physician’s orders or the instructions on the label. The next data contains solely the typical doses of this drugs. In case your dose is totally different, don’t change it except your physician tells you to take action.
The quantity of medication that you simply take relies on the power of the medication. Additionally, the variety of doses you are taking every day, the time allowed between doses, and the size of time you are taking the medication depend upon the medical drawback for which you might be utilizing the medication.
For fluid retention (edema):
For oral dosage kind (tablets):
- Adults—The same old dose is 25 to 100 milligrams (mg) every day as a single or divided dose. Your physician might want you to take this dose each different day or on 3 to five days every week.
- Kids—Dose is predicated on physique weight and should be decided by your physician.
For hypertension:
For oral dosage kind (capsule):
- Adults—At first, 12.5 milligrams (mg) or one capsule as soon as a day. Your physician might want you to take this alone or along with different blood strain medicines. Your physician might improve your dose as wanted. Nonetheless, the dose is normally no more than 50 mg per day.
- Kids—Use and dose should be decided by your physician.
For oral dosage kind (tablets):
- Adults—At first, 25 milligrams (mg) as soon as a day. Your physician might improve your dose as wanted and could also be taken as a single dose or divided into two doses.
- Kids—Dose is predicated on physique weight and should be decided by your physician.
Missed Dose
When you miss a dose of Microzide, it’s best to take the missed dose as quickly as you keep in mind. Whether it is nearly time for the following scheduled dose, it’s best to skip the dose you missed. Don’t take additional to make up for the missed dose. Doing so can improve your threat for unintended effects.
Overdose: What Occurs If I Take Too A lot Microzide?
When you take an excessive amount of Microzide, your blood strain can drop too low. Low blood strain could make you’re feeling faint or dizzy.
What Occurs If I Overdose on Microzide?
When you suppose you or another person might have overdosed on Microzide, name a healthcare supplier or the Poison Management Heart (1-800-222-1222).
If somebody collapses or is not respiratory after taking Microzide, name 911 instantly.
Precautions
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It is extremely vital that your physician test your progress at common visits to ensure this drugs is working correctly. Blood and urine checks could also be wanted to test for negative effects.
Test along with your physician immediately if in case you have seizures, decreased urine, drowsiness, dry mouth, extreme thirst, elevated coronary heart charge or pulse, muscle pains or cramps, nausea or vomiting, or uncommon tiredness or weak point. These could also be signs of a situation known as hypokalemia or potassium loss.
Test along with your physician immediately if in case you have blurred imaginative and prescient, issue in studying, eye ache, or some other change in imaginative and prescient throughout or after therapy. This might be an indication of a severe eye drawback. Your physician will need you to have your eyes checked by an ophthalmologist (eye physician).
This drugs might trigger some individuals to turn out to be dizzy. Don’t drive, use machines, or do anything that might be harmful if you’re dizzy or not alert.
Alcohol, narcotic ache relievers, or sleeping capsules might trigger you to really feel extra lightheaded, dizzy, or faint when used with this drugs. Inform your physician if you’re ingesting alcohol or utilizing ache relievers or sleeping capsules.
Earlier than you’ve any medical checks, inform the medical physician in cost that you’re taking this drugs. The outcomes of some checks (eg, checks for parathyroid operate) could also be affected by this drugs.
This drugs might improve your threat of getting pores and skin most cancers (eg, non-melanoma pores and skin most cancers). Keep away from solar publicity. Use a sunscreen if you end up open air. Keep away from sunlamps and tanning beds. Discuss to your physician if in case you have considerations about this threat.
Don’t take different medicines except they’ve been mentioned along with your physician. This contains over-the-counter (nonprescription) medicines for urge for food management, bronchial asthma, colds, cough, hay fever, or sinus issues, since they could have a tendency to extend your blood strain.
What Are Causes I Shouldn’t Take Microzide?
There are a couple of explanation why your healthcare supplier might not select Microzide as a part of your therapy plan:
- Sulfonamide allergy: An individual shouldn’t take Microzide if they’re allergic to drugs that comprise sulfonamides.
- Alcohol: Minimal use of alcohol has proven to doubtlessly lower blood strain, however ingesting an excessive amount of alcohol could cause a rise in blood strain.
- Being pregnant: Animal research haven’t proven dangerous results to the fetus when the mom takes the drug, and there should not sufficient research to point if this drug causes hurt to the fetus throughout being pregnant. Discuss to your healthcare supplier if you’re pregnant or plan to turn out to be pregnant.
- Breastfeeding: Microzide might go by means of human milk. Discuss along with your supplier if you’re breastfeeding as you could have to determine if you happen to ought to cease taking Microzide or cease breastfeeding.
- Older adults: Folks 65 years or older usually course of medication extra slowly and might have a decrease dose or a special frequency.
- Different well being circumstances: In sure people, the physique might deal with Microzide in a different way. It is best to inform your healthcare supplier if in case you have kidney issues, poor liver operate, lupus, or imaginative and prescient issues.
What Different Drugs Work together With Microzide?
Hydrochlorothiazide can work together with a number of varieties of medicine, together with:
- Corticosteroids (e.g., prednisone)
- Nonsteroidal anti-inflammatory medication (NSAIDs) (e.g., naproxen, ibuprofen)
- Lithium
- Diabetes drugs (e.g., insulin, metformin)
- Opioids (e.g., oxycodone, hydrocodone)
- Different blood strain drugs
- Sure ldl cholesterol drugs (e.g., colestipol, cholestyramine)
This checklist doesn’t embody all medication that may work together with hydrochlorothiazide. Earlier than taking hydrochlorothiazide, make sure you inform your physician about all the prescription drugs, over-the-counter drugs, nutritional vitamins, dietary supplements, and herbs you take. This may assist you to keep away from potential interactions. When you’ve got any questions on drug interactions, converse along with your physician or pharmacist.
What Drugs Are Comparable?
Microzide, a thiazide diuretic, is one sort of diuretic. Different varieties embody loop and potassium sparing.
A number of different generally prescribed diuretics embody:
- Zaroxolyn (metolazone)
- Lasix (furosemide)
- Aldactone (spironolactone)
Zaroxolyn
Metolazone oral tablets are additionally a part of the category of medicines referred to as thiazide diuretics. It’s usually prescribed to deal with hypertension and swelling from coronary heart failure and kidney illnesses.
Lasix
Furosemide oral tablets are a part of a category of medicines referred to as loop diuretics. It’s usually prescribed to deal with hypertension and swelling attributable to different circumstances like kidney illness, coronary heart failure, or liver cirrhosis. Loop diuretics assist your physique eliminate extra salt and water by rising the quantity of urine your physique makes.
In contrast with thiazide diuretics, loop diuretics may match higher for somebody with impaired kidney operate.
Aldactone
Spironolactone oral tablets are a part of a category of medicines referred to as aldosterone antagonists, or potassium-sparing diuretics. It’s usually prescribed to deal with hypertension, coronary heart failure, extreme aldosterone secretion (hyperaldosteronism), and swelling from kidney or liver issues.
Aldosterone is a chemical made within the physique that causes water retention. By blocking aldosterone, your physique received’t retain the additional fluid.
Potassium-sparing diuretics might not cut back blood strain in addition to different diuretics. They might have to be utilized in mixture with different drugs when used to deal with hypertension.
This can be a checklist of medicine from comparable courses of treatment as Microzide. It’s not a listing of medicine advisable to take with Microzide. Ask your healthcare supplier if in case you have any questions.
How Can I Keep Wholesome Whereas Taking Microzide?
Microzide is a secure and efficient treatment when used appropriately. This drug is usually used to deal with hypertension and swelling.
Whereas Microzide does have the potential for severe unintended effects akin to allergic reactions, kidney failure, or blurred imaginative and prescient, the commonest unintended effects are typically delicate. These would possibly embody low blood strain, headache, dizziness, or photosensitivity.
It is very important inform your healthcare supplier of your entire different well being circumstances and any prescription drugs, over-the-counter drugs, nutritional vitamins, dietary supplements, and herbs you take. This fashion, your supplier could make the very best choice about what drug and dose are secure and work greatest for you.
Medical Disclaimer
Verywell Well being’s drug data is supposed for training functions solely and never meant as a substitute for medical recommendation, analysis, or therapy from a healthcare skilled. Seek the advice of your physician earlier than taking any new treatment(s). IBM Watson Micromedex offers among the drug content material, as indicated on the web page.
