In partnership with Quintis
With cannabidiol (CBD oil) just lately banned from being utilized in cosmetics in China, and different markets
proscribing the usage of the oil, like the UK and Australia, cosmetics formulators are being
inspired to contemplate Indian sandalwood oil as an efficient different to CBD oil following a brand new scientific
overview revealing Indian sandalwood oil has extra substantiated advantages.
Indian sandalwood oil (Santalum album) is taken into account probably the most luxurious of all sandalwood oils and is
obtained by way of steam distillation of the tree’s fragrant heartwood. It has been used for hundreds of years in
cosmetics, corresponding to Ayurvedic skincare – topical remedies based mostly on rules of a 5000-year-old Indian well being
system – with sandalwood listed within the Charaka Samhita, an Ayurvedic Sanskrit textual content, over 2,000 years in the past.
At present, Indian sandalwood oil is quick changing into a brand new pattern ingredient in a myriad of magnificence and private care
purposes. An unlimited sustainable provide is now out there in Australia by way of firms like Quintis
Sandalwood with extra analysis being performed to show its efficacy.
To showcase the ability of Indian sandalwood oil as a substitute for CBD oil in cosmetics, Quintis Sandalwood
just lately performed a overview of present scientific research to evaluate the advantages of every.
The findings revealed
that Indian sandalwood oil has extra scientifically confirmed advantages in comparison with CBD oil making it an excellent
alternate in beauty purposes, particularly in skincare.
Dr Dhanushka Hettiarachchi, Ph.D., Product Supervisor for Quintis Sandalwood, stated Indian sandalwood oil is a
actual recreation changer for cosmetics.
“Whereas CBD oil seems to be a well-liked selection with some scientific literature out there, the vast majority of the
present CBD pores and skin exercise claims are based mostly on anecdotal proof; extra analysis is required to really show its
efficacy and efficiency.
“Indian sandalwood oil is a superb pure multipurpose ingredient for cosmetics care and
an alternate for CBD oil as it’s an efficient protecting and anti-ageing energetic ingredient, and it has
scientifically confirmed bioactivity and dermal advantages for the pores and skin together with helping with night pores and skin tone and
wound therapeutic,” says Dr Hettiarachchi.
“Indian sandalwood oil could be included in merchandise like face washes, moisturisers and serums at totally different
concentrations for deep penetrating motion and physique care merchandise like pure deodorant. Different merchandise
sandalwood oil could be utilised in is water-based facial sprays, washes and hydrogels that may be ready by
emulsifying the oil for its aroma and antioxidant pores and skin advantages.”
The scientific overview discovered Indian sandalwood oil is analogous or has extra efficacy than CBD oil throughout the
following 5 key advantages and claims that are necessary for skincare formulations:
- Wound therapeutic – Each CBD oil and Indian Sandalwood Oil act on keratinocyte proliferation to facilitate
wound therapeutic. Each do that by stimulating the calcium channels on keratinocytes, nevertheless, Indian
sandalwood oil acts particularly on the receptor OR2AT4[4], whereas CBD oil acts particularly on CBD CB-1
receptor[6]. - Pores and skin Brightening – Research have proven that Indian sandalwood oil inhibits the tyrosinase enzyme, the
key enzyme in producing melanin, which is liable for uneven pores and skin tone, darkish spots, and
pigmentation[5]. So far, there isn’t a analysis to recommend that CBD can inhibit the tyrosinase enzyme
or scale back the skins melanin manufacturing, with CBD’s brightening claims all stemming from its
antioxidant properties. - Antioxidant – Based on a research just lately revealed within the Cosmetics Journal, commissioned by
Quintis Sandalwood, Indian sandalwood oil is a potent antioxidant that works on the Keratinocytes to
shield the pores and skin from reactive oxygen species (ROS) generated by publicity to environmental
stressors corresponding to blue mild and air pollution. ROS are free radicals that trigger harm to cell construction,
breaking down collagen, decreasing elasticity and inflicting an un-even pores and skin tone [1]. CBD oil has comparable
antioxidant properties to ISO, engaged on the Keratinocytes to guard the pores and skin from reactive oxygen
species (ROS) [6,7]. - Anti-Inflammatory – Indian sandalwood oil is extensively identified for its capacity to inhibit the manufacturing of
cytokines/chemokines (IL, TNF-a) and prostaglandins, all of which trigger irritation within the pores and skin
in the end leading to pigmentation and collagen degradation. It additionally up-regulates 11βHSD1 enzyme
to covert inflammatory cortisone to inactive cortisol [2,3,4]. CBD stimulates the CB-2 receptors in pores and skin
to scale back cytokine chemokine, nevertheless, the mechanism stays ambiguous [6,7]. - Anti-ageing – Indian sandalwood oil is discovered to inhibit the MMP1 enzyme generated within the pores and skin when a
particular person is uncovered to sure inside (way of life) and environmental stressors. The MMP1 enzyme is
liable for breaking down collagen[1]. A discount in collagen can lead to elevated effective
strains/wrinkles and reduces pores and skin elasticity and thickness. So far, there isn’t a analysis to recommend that
CBD can inhibit the MMP1 enzyme, with CBD’s anti-aging claims all stemming from its antioxidant
properties[6].
“Our Indian sandalwood oil has over 20 worldwide certifications together with being accepted on the Chinese language
Stock of Current Cosmetics Elements, it’s listed as a protected ingredient with the US Meals & Drug
Administration (FDA), and assembly the requirements of the British Pharmacopoeia, so there may be nice alternative
for this treasured, medicinal ingredient to be thought-about a high-quality substitute for CBD oil.
From its pores and skin
advantages corresponding to anti-tyrosinase and antimicrobial actions, by way of to its calming properties, Indian
sandalwood oil is the proper ingredient for holistic cosmetics purposes,” says Dr Hettiarachchi.
Indian sandalwood oil samples could be requested by way of the Quintis Sandalwood website.
References:
1. Francois-Newton, V., et al. (2021). “Antioxidant and Anti-Ageing Potential of Indian Sandalwood Oil towards Environmental Stressors In
Vitro and Ex Vivo.” Cosmetics 8(2): 53.
2. Sharma, M., et al. (2018). “East Indian sandalwood oil is a phosphodiesterase inhibitor: A brand new therapeutic choice within the therapy of
inflammatory pores and skin illness.” Frontiers in Pharmacology 9: 200.
3. Sharma, M., et al. (2014). “Suppression of Lipopolysaccharide‐stimulated Cytokine/Chemokine Manufacturing in Pores and skin Cells by
Sandalwood Oils and Purified α‐santalol and β‐santalol.” Phytotherapy analysis 28(6): 925-932.
4. Moy, R. L. and C. Levenson (2017). “Sandalwood album oil as a botanical therapeutic in dermatology.” The Journal of medical and
aesthetic dermatology 10(10): 34.
5. Misra, B. B. and S. Dey (2013). “TLC-bioautographic analysis of in vitro anti-tyrosinase and anti-cholinesterase potentials of
sandalwood oil.” Pure Product Communications 8(2): 1934578X1300800231.
6. Baswan, S.M., Klosner, A.E., Glynn, Okay., Rajgopal, A., Malik, Okay., Yim, S. and Stern, N. (2020). “Therapeutic potential of Cannabidiol
(CBD) for pores and skin well being and issues. Medical, beauty and investigational dermatology, 13, 927.
7. Liu, C., Li, H., Xu, F., Jiang, X., Ma, H. and Seeram, N.P. (2021). “Cannabidiol Protects Human Pores and skin Keratinocytes from Hydrogen-
Peroxide-Induced Oxidative Stress through Modulation of the Caspase-1–IL-1β Axis”. Journal of Pure Merchandise, 84(5), 1563.
