Frequently consuming tea could decrease the danger of growing rheumatoid arthritis (RA), particularly for present people who smoke and in anti-citrullinated autoantibody (ACPA)-positive RA, in keeping with a examine printed in Arthritis & Analysis Remedy.1
“Lately, food regimen has gained consideration for its potential immunomodulatory results. After water, tea is the preferred drink on this planet [and] every kind of tea are wealthy in polyphenols, that are antioxidants which will scale back the danger of inflammatory ailments comparable to RA,” investigators defined. “Nonetheless, research on tea consumption and the danger of growing RA have to date proven inconclusive outcomes.”
Information from the population-based, case-control examine, EIRA, was collected for 2237 sufferers with RA identified between 2005 and 2018 and 4661 controls that have been matched for age, intercourse, and residential space. Participation charge was 90% for the RA cohort and 69% for the controls.
Tea consumption was categorised as no (0 cups/day), irregular (< 1 cup/day), common (1-2 cups/day), and excessive (≥ 2 cups/day). Natural tea was categorised as no (0 cups/day), irregular (< 1 cup/day), and common (≥1 cup/day).
Outcomes have been adjusted for way of life elements, comparable to smoking habits, alcohol consumption, and low consumption, in addition to physique mass index, and academic stage.
The management group was extra more likely to be excessive shoppers of tea when put next with the RA cohort (22.1% vs 19.7%, respectively). Within the RA group, 57.3% drank tea and 19.7% have been categorised into the excessive tea consumption class. A complete of 58.4% of contributors within the management group drank tea and 22.1% have been excessive tea shoppers. Moreover, those that have been tea shoppers have been much less more likely to smoke or drink espresso and had a decrease alcohol consumption. Smoking was extra prevalent within the RA cohort (22.5% vs 13.8%).
Whereas tea consumption and threat of RA was not linear, there was a discount in odds for many who consumed 1 or extra cups per day. Excessive consumption was related to a 22% decrease threat when put next with irregular shoppers. Nonetheless, after adjusting for covariates, outcomes have been now not statistically vital. Individuals who frequently drank natural tea had a borderline statistically discount in threat of growing RA when put next with irregular shoppers (adjOR = 0.77, 95% CI 0.58–1.02).
The chances of growing ACPA-positive RA have been considerably decrease within the excessive tea shopper group when put next with irregular tea shoppers (adjOR = 0.76, 95% CI 0.62–0.94). Lowest odds ratio was seen in present people who smoke (adjOR = 0.60, 95% CI 0.38–0.95).
The examine was strengthened by the participation charges and examine design. Nonetheless, tea consumption knowledge was lacking for a big proportion of contributors, which investigators selected to categorise within the no tea consumption group. This notion was backed up by the truth that proportion of tea drinkers was consistent with Swedish statistics on tea gross sales. Irregular tea consumption was used as a reference. Recall bias could have altered the outcomes of the examine; nevertheless, it was not believed to have impacted the quantity of lacking knowledge as percentages have been related in each the RA cohort and the management group.
“This examine confirmed an inverse affiliation with the danger of RA amongst excessive tea shoppers in comparison with irregular shoppers amongst people who smoke and within the ACPA-positive subset of RA,” investigators concluded. “We couldn’t draw any conclusion about no tea consumption and the danger of RA, because of the opportunity of bias.”
Reference:
Westerlind H, Palmqvist I, Saevarsdottir S, Alfredsson L, Klareskog L, Di Giuseppe D. Is tea consumption related to discount of threat of rheumatoid arthritis? A Swedish case-control examine. Arthritis Res Ther. 2021;23(1):209. Revealed 2021 Aug 7. doi:10.1186/s13075-021-02583-y
